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Pelvic inflammatory disease PID occurs when an infection spreads from the vagina to the cervix and fallopian tubes Allergic reaction to packaged food. Hormonal changes Contraception such as the pill, injection or IUD intrauterine device Infection in the vagina or uterus Fibroids or polyps inside the uterus Trauma to the vagina Some medications such as anticoagulants or anti-epilepsy drugs Underlying health problems such as bleeding or thyroid disorders Cancer in the lining of the uterus, the cervix or vagina rare. This allows the passage of water and water-soluble substances through the tissue. Dewhurst's Textbook of Obstetrics and Gynaecology. If the boil is filled with pus and appears severely infected, a doctor may drain the boil using a special sterile needle.